Articles & guides — page 4

92 cited, vendor-independent pieces on the questions people actually ask — reconstitution and handling, half-lives, compound comparisons, and how to track a protocol. Research and education only; never dosing advice, never sourcing.

92 articles

Compound overviews4 min

What is ipamorelin?

Ipamorelin explained with the literature: a five-amino-acid peptide that triggers a pulse of your own growth hormone, why "selective" is its whole story, and an honest look at a mostly preclinical evidence base.

Preclinical
Compound overviews4 min

What is CJC-1295?

CJC-1295 explained with the human data: a GHRH analog, the crucial DAC vs no-DAC fork, and the 2006 trial that measured a 6–8 day half-life and days-long IGF-1 rises in healthy adults.

Human clinical data
Compound overviews3 min

What is semaglutide?

Semaglutide explained plainly: how this GLP-1 medication mimics a gut hormone, what the big human trials actually showed (STEP 1: ~15% weight loss), and the brands it sells under.

Approved medicine
Compound overviews3 min

What is tirzepatide?

Tirzepatide explained plainly: the "twincretin" that hits two gut-hormone receptors, why it is called imbalanced, and what SURMOUNT-1 showed (up to ~21% weight loss).

Approved medicine
Compound overviews3 min

What is tesamorelin?

Tesamorelin explained: a stabilised GHRH analog and — unlike most peptides in its family — an FDA-approved medicine (Egrifta), with the HIV lipodystrophy trials that got it there.

Approved medicine
Compound overviews3 min

What is sermorelin?

Sermorelin explained: the shortest fully-active GHRH fragment, its history as the approved drug Geref, how it relates to CJC-1295, and its status today as a compounded peptide.

Human clinical data
Compound overviews3 min

What is HCG?

HCG explained: human chorionic gonadotropin, why it acts like luteinizing hormone, why it is dosed in International Units instead of milligrams, and its TRT-adjacent research context.

Approved medicine
Compound overviews3 min

What is anastrozole?

Anastrozole explained: an aromatase inhibitor that blocks testosterone-to-estrogen conversion, its ~50-hour half-life from the FDA label, and its TRT-adjacent research context. Education only.

Approved medicine
Compound overviews3 min

What is testosterone cypionate?

Testosterone cypionate explained: plain testosterone plus an ester that controls its release, why that stretches the half-life to about 8 days, and how it compares to enanthate.

Approved medicine
Compound overviews3 min

What are research peptides?

A plain-language primer on research peptides: what a peptide actually is, what "research compound" honestly means, the main families, and how to read the wildly different evidence behind each.

Concept / method
Compound overviews4 min

What is retatrutide?

Retatrutide explained plainly: the investigational "triple G" agonist that hits three hormone receptors — GIP, GLP-1, and glucagon — and what its phase-2 trials showed (~24% weight loss).

Human clinical data
Compound overviews5 min

What is GHK-Cu (copper peptide)?

GHK-Cu explained with the literature: the copper tripeptide Pickart discovered in 1973, what cell and topical-skin studies show for collagen and wound healing, and why injectable evidence is thin.

Preclinical

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