Half-lives / Gonadorelin

Gonadorelin half-life

≈ 10–40 min (0.4 hours) — computed decay curve below, primary source cited.

50% · 0h02h (≈5 half-lives)
Single-dose relative level over time, computed from the published Gonadorelin half-life (0.4 h). An estimate from population values — individual pharmacokinetics vary.
Half-life≈ 10–40 min
~97% cleared (5 half-lives)0.1 days
Typical route (published research)SubQ · research

Source: GnRH pharmacology (Belchetz 1978, PMID 100883); terminal half-life 10–40 min

Frequently asked

How long does Gonadorelin stay in your system?

With a half-life of ≈ 10–40 min, roughly 97% of a single Gonadorelin dose is cleared after five half-lives — about 0.1 days. Repeated dosing accumulates and takes correspondingly longer to clear.

What does a ≈ 10–40 min half-life mean in practice?

Every 10–40 min, the remaining amount halves: 100% → 50% → 25% → 12.5%, and so on. The curve above plots exactly this decay for a single dose.

Where does this Gonadorelin half-life number come from?

GnRH pharmacology (Belchetz 1978, PMID 100883); terminal half-life 10–40 min. We cite a primary source for every half-life we publish and version every change.

Related: Gonadorelin reconstitution calculator · Gonadorelin dose charts

Guides mentioning Gonadorelin

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