Half-lives / PT-141

PT-141 half-life

≈ 2.7 h (2.7 hours) — computed decay curve below, primary source cited.

50% · 3h014h (≈5 half-lives)
Single-dose relative level over time, computed from the published PT-141 half-life (2.7 h). An estimate from population values — individual pharmacokinetics vary.
Half-life≈ 2.7 h
~97% cleared (5 half-lives)0.6 days
Typical route (published research)SubQ · as studied

Source: FDA VYLEESI (bremelanotide) label, NDA 210557 (2019); plasma half-life ≈ 2.7 h

Frequently asked

How long does PT-141 stay in your system?

With a half-life of ≈ 2.7 h, roughly 97% of a single PT-141 dose is cleared after five half-lives — about 0.6 days. Repeated dosing accumulates and takes correspondingly longer to clear.

What does a ≈ 2.7 h half-life mean in practice?

Every 2.7 h, the remaining amount halves: 100% → 50% → 25% → 12.5%, and so on. The curve above plots exactly this decay for a single dose.

Where does this PT-141 half-life number come from?

FDA VYLEESI (bremelanotide) label, NDA 210557 (2019); plasma half-life ≈ 2.7 h. We cite a primary source for every half-life we publish and version every change.

Related: PT-141 reconstitution calculator · PT-141 dose charts

Guides mentioning PT-141

See your own estimated levels

The Zyra Labs app plots this curve from the doses you actually log — accumulation, overlaps, and all — on your device, free to start.

Open Zyra Labs

Zyra Labs is a research and educational utility. Nothing on this page is medical advice, a dosing recommendation, or an endorsement of any compound. We never sell or source compounds and refuse sourcing questions. Consult a qualified clinician for decisions about your health.