Half-lives / SS-31 (Elamipretide)

SS-31 (Elamipretide) half-life

≈ 4 h (4 hours) — computed decay curve below, primary source cited.

50% · 4h020h (≈5 half-lives)
Single-dose relative level over time, computed from the published SS-31 (Elamipretide) half-life (4 h). An estimate from population values — individual pharmacokinetics vary.
Half-life≈ 4 h
~97% cleared (5 half-lives)0.8 days
Typical route (published research)SubQ · research

Source: Elamipretide (SS-31) SubQ PK ≈ 4 h; FDA accelerated approval 2025 (Barth syndrome)

Frequently asked

How long does SS-31 (Elamipretide) stay in your system?

With a half-life of ≈ 4 h, roughly 97% of a single SS-31 (Elamipretide) dose is cleared after five half-lives — about 0.8 days. Repeated dosing accumulates and takes correspondingly longer to clear.

What does a ≈ 4 h half-life mean in practice?

Every 4 h, the remaining amount halves: 100% → 50% → 25% → 12.5%, and so on. The curve above plots exactly this decay for a single dose.

Where does this SS-31 (Elamipretide) half-life number come from?

Elamipretide (SS-31) SubQ PK ≈ 4 h; FDA accelerated approval 2025 (Barth syndrome). We cite a primary source for every half-life we publish and version every change.

Related: SS-31 (Elamipretide) reconstitution calculator · SS-31 (Elamipretide) dose charts

Guides mentioning SS-31 (Elamipretide)

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