Half-lives / TB-500

TB-500 half-life

≈ 2–3 days (60 hours ≈ 2.5 days) — computed decay curve below, primary source cited.

50% · 3d013d (≈5 half-lives)
Single-dose relative level over time, computed from the published TB-500 half-life (60 h). An estimate from population values — individual pharmacokinetics vary.
Half-life≈ 2–3 days
~97% cleared (5 half-lives)12.5 days
Typical route (published research)SubQ · 2×/week

Source: Thymosin β4 pharmacokinetic literature (see monograph)

Frequently asked

How long does TB-500 stay in your system?

With a half-life of ≈ 2–3 days, roughly 97% of a single TB-500 dose is cleared after five half-lives — about 12.5 days. Repeated dosing accumulates and takes correspondingly longer to clear.

What does a ≈ 2–3 days half-life mean in practice?

Every 2–3 days, the remaining amount halves: 100% → 50% → 25% → 12.5%, and so on. The curve above plots exactly this decay for a single dose.

Where does this TB-500 half-life number come from?

Thymosin β4 pharmacokinetic literature (see monograph). We cite a primary source for every half-life we publish and version every change.

Related: TB-500 reconstitution calculator · TB-500 dose charts

Guides mentioning TB-500

See your own estimated levels

The Zyra Labs app plots this curve from the doses you actually log — accumulation, overlaps, and all — on your device, free to start.

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